Publications

2018

Mamoru Sasaki, Shotaro Chubachi, Naofumi Kameyama, Minako Sato, Mizuha Haraguchi, Masaki Miyazaki, Saeko Takahashi, Takayoshi Nakano, Yukiko Kuroda, Tomoko Betsuyaku, Koichi Matsuo
Effects of long-term cigarette smoke exposure on bone metabolism, structure, and quality in a mouse model of emphysema
PLOS ONE. 2018 Jan 30;13(1):e0191611. doi: 10.1371/journal.pone.0191611. eCollection 2018. PMID: 29381718.

2017

Hidenori Matsui, Tetsufumi Takahashi, Somay Y. Murayama, Marina Kawaguchi, Koichi Matsuo, and Masahiko Nakamura.
Protective Efficacy of a Hydroxy Fatty Acid against Gastric Helicobacter Infections.
Helicobacter 2017 Dec; 22(6). doi: 10.1111/hel.12430. PMID: 28834011.

Mengyu Yang, Atsushi Arai, Nobuyuki Udagawa, Toru Hiraga, Zhao Lijuan, Susumu Ito, Toshihisa Komori, Takeshi Moriishi, Koichi Matsuo, Kouji Shimoda, Ali Zahalka, Yasuhiro Kobayashi, Naoyuki Takahashi, and Toshide Mizoguchi.
Osteogenic Factor Runx2 Marks a Subset of Leptin Receptor-Positive Cells that Sit Atop the Bone Marrow Stromal Cell Hierarchy.
Sci Rep. 7(1):4928. doi: 10.1038/s41598-017-05401-1. PMID: 28694469.

Minjie Li, Chengfei Zhang, Li Jian Jin, Koichi Matsuo, and Yanqi Yang.
P. gingivalis Lipopolysaccharide regulates Ephrin/Eph Signalling in Human Periodontal Ligament Fibroblasts.
J Periodontal Res. 2017 Oct;52(5):913-921. doi: 10.1111/jre.12463. PMID: 28590061.

Ayako Sakamoto, Yukiko Kuroda, Sho Kanzaki, and Koichi Matsuo.
Dissection of the auditory bulla in postnatal mice: Isolation of the middle ear bones and histological analysis.
J. Vis. Exp. 2017 Jan 4;(119). doi: 10.3791/55054. PMID: 28117786.

Kamel W, Sugihara E, Nobusue H, Yamaguchi-Iwai S, Onishi N, Maki K, Fukuchi Y, Matsuo K, Muto A, Saya H, and Shimizu T.
Simvastatin-induced apoptosis in osteosarcoma cells: a key role of RhoA-AMPK-p38 MAPK signaling in antitumor activity.
Mol Cancer Ther. 2017 Jan;16(1):182-192. doi:10.1158/1535-7163.MCT-16-0499. PMID: 27799356.

2016

Hidenori Matsui, Yuriko Nakatani, Haruno Yoshida, Asako Takizawa, Osamu Takeuchi, Anders Øverby, Takashi Takahashi, Somay Y. Murayama, and Koichi Matsuo.
Flesh-eating Streptococcus pyogenes triggers the expression of receptor activator of nuclear factor-kappaB ligand.
Cellular Microbiology. 2016 Oct;18(10):1390-404. DOI: 10.1111/cmi.12581. PMID: 26894505.

Nobuhito Nango, Shogo Kubota, Tomoka Hasegawa, Wataru Yashiro, Atsushi Momose, and Koichi Matsuo.
Osteocyte-directed bone demineralization along canaliculi.
Bone. 2016; 84, 279-288. doi: 10.1016/j.bone.2015.12.006.
(This article is Open Access). PMID: 26709236.

Yukiko Kuroda, Kenta Maruyama, Hideki Fujii, Isamu Sugawara, Shigeru B. H. Ko, Hisataka Yasuda, Hidenori Matsui, and Koichi Matsuo.
Osteoprotegerin regulates pancreatic beta-cell homeostasis upon microbial invasion.
PLOS ONE. 2016 Jan 11;11(1):e0146544.
(This article is Open Access). PMID: 26751951.

2015

Koichi Matsuo, Yukiko Kuroda, Nobuhito Nango, Kouji Shimoda, Yoshiaki Kubota, Masatsugu Ema, Latifa Bakiri, Erwin F Wagner, Yoshihiro Takeda, Wataru Yashiro, and Atsushi Momose.
Osteogenic capillaries orchestrate growth plate-independent ossification of the malleus.
Development. 2015 Nov 15;142(22):3912-20. doi: 10.1242/dev.123885. Epub 2015 Oct 1.
(This article is Open Access) PMID: 26428006.

Thao Nguyen, Agnieszka Arthur, Romana Panagopoulos, Sharon Paton, John D. Hayball, Andrew Zannettino, Louise Purton, Koichi Matsuo, and Stan Gronthos.
EphB4 expressing stromal cells exhibit an enhanced capacity for hematopoietic stem cell maintenance.
Stem Cells. 2015; 33(9):2838-49. doi: 10.1002/stem.2069. PMID: 26033476

Omata Y, Yasui T, Hirose J, Izawa N, Imai Y, Matsumoto T, Masuda H, Tokuyama N, Nakamura S, Tsutsumi S, Yasuda H, Okamoto K, Takayanagi H, Hikita A, Imamura T, Matsuo K, Saito T, Kadono Y, Aburatani H, and Tanaka S.
Genomewide Comprehensive Analysis Reveals Caitical Cooperation Between Smad and c-Fos in RANKL-Induced Osteoclastogenesis.
J Bone Miner Res. 2015;30(5):869-877. doi:10.1002/jbmr.2418. PMID: 25431176

Valverde-Franco G, Hum D, Matsuo K, Lussier B, Pelletier JP, Fahmi H, Kapoor M, and Martel-Pelletier J.
The in vivo effect of prophylactic subchondral bone protection of osteoarthritic synovial membrane in bone-specific Ephb4-overexpressing mice.
Am J Pathol. 2015;185(2):335-46. doi:10.1016/j.ajpath.2014.10.004. PMID: 25453723

Matsushita M, Ozaki Y, Hasegawa Y, Terada F, Tabata N, Shiheido H, Yanagawa H, Oikawa T, Matsuo K, Du W, Yamada T, Hozumi M, Ichikawa D, and Hattori Y.
A novel phthalimide derivative, TC11, has preclinical effects on high-risk myeloma cells and osteoclasts.
PLoS One. 2015;10(1):e0116135. doi:10.1371/journal.pone.0116135. eCollection 2015. PMID: 25617756

2014

Akiyama N, Shinzawa M, Miyauchi M, Yanai H, Tateishi R, Shimo Y, Ohshima D, Matsuo K, Sasaki I, Hoshino K, Wu G, Yagi S, Inoue J, Kaisho T, and Akiyama T.
Limitation of immune tolerance-inducing thymic epithelial cell development by Spi-B-mediated negative feedback regulation.
J Exp Med. 2014;211(12):2425-2438. doi: 10.1084/jem.20141207. PMID: 25385757

Shimizu T, Sugihara E, Yamaguchi-Iwai S, Tamaki S, Koyama Y, Kamel W, Ueki A, Ishikawa T, Chiyoda T, Osuka S, Onishi N, Ikeda H, Kamei J, Matsuo K, Fukuchi Y, Nagai T, Toguchida J, Toyama Y, Muto A, and Saya H.
IGF2 preserves osteosarcoma cell survival by creating an autophagic state of dormancy that protects cells against chemotherapeutic stress.
Cancer Res. 2014;74(22):6531-6541. PMID: 25273088

Bunjobpol W, Dulloo I, Igarashi K, Concin N, Matsuo K, and Sabapathy K.
Suppression of acetylpolyamine oxidase by selected AP-1 members regulates DNp73 abundance: mechanistic insights for overcoming DNp73-mediated resistance to chemotherapeutic drugs.
Cell Death Differ. 2014;21(8):1240-1249. PMID: 24722210

Negishi N, Suzuki D, Ito R, Irie N, Matsuo K, Yahata T, Nagano K, Aoki K, Ohya K, Hozumi K, Ando K, Tamaoki N, Ito M, and Habu S.
Effective expansion of engrafted human hematopoietic stem cells in bone marrow of mice expressing human Jagged-1.
Exp Hematol. 2014;42(6):487-494. PMID: 24530466

2013
Oikawa T, Nakamura A, Onishi N, Yamada T, Matsuo K, and Saya H.
Acquired expression of NFATc1 downregulates E-Cadherin and promotes cancer cell invasion.
Cancer research. 2013;73(16):5100-5109. PMID: 23811942

Nobuhito Nango, Shogo Kubota, Akihisa Takeuchi, Yoshio Suzuki, Wataru Yashiro, Atsushi Momose, and Koichi Matsuo.
Talbot-defocus multiscan tomography using the synchrotron X-ray microscope to study the lacuno-canalicular network in mouse bone
Biomed Opt Express. 2013;4(6):917-923. PMID: 23761853

Oikawa T, Kuroda Y, and Matsuo K. (review)
Regulation of osteoclasts by membrane-derived lipid mediators.
Cell Mol Life Sci. 2013;70:3341-3353. PMID: 23296124

Arthur A, Panagopoulos RA, Cooper L, Menicanin D, Parkinson IH, Codrington JD, Vandyke K, Zannettino AC, Koblar SA, Sims NA, Matsuo K, and Gronthos S.
EphB4 enhances the process of endochondral ossification and inhibits remodelling during bone fracture repair.
J Bone Miner Res. 2013;28(4):926-935. doi: 10.1002/jbmr.1821. PMID: 23165754

2012

Kuroda Y, and Matsuo K. (review)
Molecular mechanisms of triggering, amplifying and targeting RANK signaling in osteoclasts.
World J Orthop. 2012;3(11):167-174. doi: 10.5312/wjo.v3.i11.167. PMID: 23330071

Tsukasa Oikawa, Masaaki Oyama, Hiroko Kozuka-Hata, Shunsuke Uehara, Nobuyuki Udagawa, Hideyuki Saya, and Koichi Matsuo.
Tks5-dependent formation of circumferential podosomes/invadopodia mediates cell–cell fusion.
J Cell Biol. 2012;197(4):553-568. PMID: 22584907

Kuroda Y, Hisatsune C, Mizutani A, Ogawa N, Matsuo K, and Mikoshiba K.
Cot Kinase promotes Ca2+ oscillation/calcineurin-independent osteoclastogenesis by stabilizing NFATc1 protein.
Mol Cell Biol. 2012;32(14):2954-2963. PMID: 22615493

Matsuo K, and Otaki N. Rreview)
Bone cell interactions through Eph-ephrin: Bone modeling, remodeling and associated diseases.
Cell Adh Migr. 2012;6(2):148-156. PMID: 22660185

Shinichiro Nakada, Rikako Miyamoto Yonamine, and Koichi Matsuo
RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1
Cancer Research. 2012;72(19):4974-4983. doi: 10.1158/0008-5472.CAN-12-1057 PMID: 22865450

Koichi Matsuo (review)
Osteocytes Communicate with Osteoclast Lineage Cells via RANKL.
IBMS BoneKEy 9, Article number: 39. doi:10.1038/bonekey.2012.36 Published online 29 Feb 2012

Nobuhito Nango, Shogo Kubota, Wataru Yashiro, Atsushi Momose, Yasunari Takada, and Koichi Matsuo
Constructing a multi-scan synchrotron X-ray microscope to study the function of osteocyte canaliculi in mouse bone
AIP Conf. Proc. 2012?1466:199-204. doi: 10.1063/1.4742292

Valverde-Franco G, Pelletier JP, Fahmi H, Hum D, Matsuo K, Lussier B, Kapoor M, and Martel-Pelletier J.
In vivo bone-specific EphB4 overexpression in mice protects both subchondral bone and cartilage during osteoarthritis.
Arthritis Rheum. 2012;64(11):3614-3625. doi: 10.1002/art.34638. PMID:22833446

Ito R, Negishi N, Irie N, Matsuo K, Suzuki D, Katano I, Hayakawa E, Kawai K, Kamisako T, Eto T, Ogura T, Hozumi K, Ando K, Aiso S, Tamaoki N, Habu S, and Ito M.
Osteosclerosis and inhibition of human hematopoiesis in NOG mice expressing human Delta-like 1 in osteoblasts.
Exp Hematol. 2012, 40(11):953-963.e3. doi:10.1016/j.exphem.2012.07.002. PMID: 22771497

Takada Y, and Matsuo K.
Gefitinib, but not erlotinib, is a possible inducer of Fra-1-mediated interstitial lung disease.
Keio J Med. 2012;61(4):120-127. PMID: 23324306

2011

Yasunari Takada, Lionel Gresh, Aline Bozec, Eiji Ikeda, Kazunori Kamiya, Masazumi Watanabe, Koichi Kobayashi, Koichiro Asano, Yoshiaki Toyama, Erwin F. Wagner, and Koichi Matsuo. (2011)
Interstitial lung disease induced by gefitinib and Toll-like receptor ligands is mediated by Fra-1.
Oncogene 30,?3821-3832. PubMed

Sho Kanzaki, Yasunari Takada, Shumpei Niida, Yoshihiro Takeda, Nobuyuki Udagawa, Kaoru Ogawa, Nobuhito Nango, Atsushi Momose, and Koichi Matsuo. (2011) Impaired vibration of auditory ossicles in osteopetrotic mice.
Am J Pathol. 178, 1270-1278. PubMed

Agnieszka Arthur, Andrew. C Zannettino, Romana Panagopoulos, Simon A Koblar, Natalie A Sims, Con Stylianou, Koichi Matsuo, and Stan Gronthos. (2011) EphB/ephrin-B interactions mediate human MSC attachment, migration and osteochondral Differentiation.
Bone 48, 533-542. PubMed

Yoshida H, Matsui H, Murayama SY, Takada Y, Matsuo K, Takahashi T, Nakamura M, Ubukata K, and Takahashi T. (2011)
A CD46 transgenic mouse model for studying the histopathology of arthritis caused by subcutaneous infection with Streptococcus dysgalactiae subspecies equisimilis (SDSE).
J Med Microbiol, 60(Pt 12):1860-1868. PubMed

2010

Yasunari Takada, Neelanjan Ray, Eiji Ikeda, Tomohiro Kawaguchi, Masayoshi Kuwahara, Erwin F. Wagner, and Koichi Matsuo.  (2010) Fos proteins suppress dextran sulfate sodium-induced colitis through inhibition of NF-?B. J. Immunol. 184:1014-1021. PubMed

Koichi Matsuo. (2010) Eph and ephrin interactions in bone. Adv. Exp. Med. Biol. 658, 95-103. PubMed

2009

Irie N, Takada Y, Watanabe Y, Matsuzaki Y, Naruse C, Asano M, Iwakura Y, Suda T, and Matsuo K. (2009) Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis. J. Biol. Chem. 284:14637-14644.  PubMed

Yamaguchi T, Takada Y, Maruyama K, Shimoda K, Arai Y, Nango N, Kosaki N, Takaishi H, Toyama Y, and Matsuo K. (2009) Fra-1/AP-1 impairs inflammatory responses and chondrogenesis in fracture healing. J. Bone Miner. Res. 24:2056-2065. PubMed

Kanzaki S, Takada Y, Ogawa K,and Matsuo K. (2009) Bisphosphonate therapy ameliorates hearing loss in mice lacking osteoprotegerin. J. Bone Miner. Res. 24:43-49. PubMed

Matsuo K. (2009) Cross-talk among bone cells. Curr. Opin. Nephrol. Hypertens. 18, 292-297. PubMed

Furukawa M, Takaishi H, Takito J, Yoda M, Sakai S, Hikata T, Hakozaki A, Uchikawa S, Matsumoto M, Chiba K, Kimura T, Okada Y, Matsuo K, Yoshida H, and Toyama Y. (2009) IL-27 abrogates receptor activator of NF-kappaB ligand-mediated osteoclastogenesis of human granulocyte-macrophage colony-forming unit cells through STAT1-dependent inhibition of c-Fos. J. Immunol. 183:2397-2406. PubMed

Kim JH, Jin HM, Kim K, Song I, Youn BU, Matsuo K, and Kim N. (2009) The Mechanism of Osteoclast Differentiation Induced by IL-1. J. Immunol. 183:1862-1870. PubMed

2008

Matsuo K, and Irie N. (2008) Osteoclast-osteoblast communication. Arch. Biochem. Biophys. 473:201-209. PubMed (Arch. Biochem. Biophys. Top Cited Article 2008-2010)

Selvarajoo K, Takada Y, Gohda J, Helmy M, Akira S, Tomita M, Tsuchiya M, Inoue J, and Matsuo K. (2008) Signaling flux redistribution at Toll-like receptor pathway junctions. PLoS ONE 3(10): e3430. PubMed

Kuroda Y, Hisatsune C, Nakamura T, Matsuo K, and Mikoshiba K. (2008) Osteoblasts induce Ca2+ oscillation-independent NFATc1 activation during osteoclastogenesis. Proc. Natl. Acad. Sci. USA 105:8643-8648. PubMed

Hikosaka Y, Nitta T, Ohigashi I, Yano K, Ishimaru N, Hayashi Y, Matsumoto M, Matsuo K, Penninger JM, Takayanagi H, Yokota Y, Yamada H, Yoshikai Y, Inoue J, Akiyama T, and Takahama Y. (2008) The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator. Immunity 29:438-450. PubMed

Hamdi M, Popeijus HE, Carlotti F, Janssen JM, van der Burgt C, Cornelissen-Steijger P, van de Water B, Hoeben RC, Matsuo K, and van Dam H. (2008) ATF3 and Fra1 have opposite functions in JNK- and ERK-dependent DNA damage responses. DNA Repair 7:487-496. PubMed

2007

Yamashita T, Yao Z, Li F, Zhang Q, Badell R, Schwarz EM, Takeshita S, Wagner EF, Noda M, Matsuo K, Xing L, and Boyce BF. (2007) NF-?B p50 and p52 regulate receptor activator of NF-kappaB ligand (RANKL) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-Fos and NFATc1. J. Biol. Chem. 282:18245-18253. PubMed

Yagi M, Ninomiya K, Fujita N, Suzuki T, Iwasaki R, Morita K, Hosogane N, Matsuo K, Toyama Y, Suda T, and Miyamoto T. (2007) Induction of DC-STAMP by alternative activation and downstream signaling mechanisms. J. Bone Miner. Res. 22:992-1001. PubMed

Sano G, Takada Y, Goto S, Maruyama K, Oka K, Shindo Y, Matsui H, and Matsuo K. (2007) Flagella facilitate escape of Salmonella from oncotic macrophages. J. Bacteriol. 189:8224-8232. PubMed

Maruyama K, Sano G, Ray N, Takada Y, and Matsuo K. (2007) c-Fos-deficient mice are susceptible to Salmonella enterica serovar Typhimurium infection. Infect. Immun. 75:1520-1523. PubMed

2006

**Zhao C, Irie N, Takada Y, Shimoda K, Miyamoto T, Nishiwaki T, Suda T, and Matsuo K. (2006) Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis. Cell Metab. 4:111-121. PubMed

Featured in: Mundy GR, and Elefteriou F. (2006) Boning up on Ephrin Signaling. Cell 126:441-443.  PubMed Andrew, N.A. (2006) Bidirectional Signaling in bone. BoneKEy-Osteovision 3, 6-9.

Kanzaki S, Ito M, Takada Y, Ogawa K, and Matsuo K. (2006) Resorption of auditory ossicles and hearing loss in mice lacking osteoprotegerin. Bone 39:414-419. PubMed

Ray N, Kuwahara M, Takada Y, Maruyama K, Kawaguchi T, Tsubone H, Ishikawa H, and Matsuo K. (2006) c-Fos suppresses systemic inflammatory response to endotoxin. Int. Immunol. 18:671-677. PubMed

Nishiwaki T, Yamaguchi T, Zhao C, Amano H, Hankenson KD, Bornstein P, Toyama Y, and Matsuo K. (2006) Reduced expression of thrombospondins and craniofacial dysmorphism in mice overexpressing Fra1. J. Bone Miner. Res. 21:596-604. PubMed

Maruyama K, Sano G, and Matsuo K. (2006) Murine osteoblasts respond to LPS and IFN-gamma similarly to macrophages. J. Bone Miner. Metab. 24:454-460. PubMed

Maruyama K, Takada Y, Ray N, Kishimoto Y, Penninger JM, Yasuda H, and Matsuo K. (2006) Receptor activator of NF-kappaB ligand and osteoprotegerin regulate proinflammatory cytokine production in mice. J. Immunol. 177:3799-3805. PubMed